Scale-Up Studies on High Shear Wet Granulation Process from Mini-Scale to Commercial Scale

Scale-up studies on high shear wet granulation process from mini-scale to commercial scale.

A newly developed mini-scale high shear granulator was used for scale-up study of wet granulation process from 0.2 to 200 L scales. Under various operation conditions and granulation bowl sizes, powder mixture composed of anhydrous caffeine, D-mannitol, dibasic calcium phosphate, pregelatinized starch and corn starch was granulated by adding water. The granules were tabletted, and disintegratio...

Wet Granulation: End-Point Determination and Scale-Up

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A Scaling-up Synthesis from Laboratory Scale to Pilot Scale and to near Commercial Scale for Paste-Glue Production

This paper concerns on developing a synthesis method of paste-glue production for gummed tape using a corn-based starch as an alternative feedstock from laboratory-scale to pilot-scale and to near commercial scale. Basically, two methods of synthesis were developed to produce paste-glue in laboratory scale. Based on the two methods, we then scale-up the earlier laboratory scale data to pilot-sc...

Production Scale Up of Nanofibers: A Review

Climate Change Impact on Precipitation Extreme Events in Uncertainty Situation; Passing from Global Scale to Regional Scale

Global warming and then climate change are important topics studied by researchers throughout the world in the recent decades. In these studies, climatic parameters changes are investigated. Considering large-scaled output of AOGCMs and low precision in computational cells, uncertainty analysis is one of the principles in doing hydrological studies. For this reason, it is tried that investigati...